10 Best Mouse With Side Buttons in 2026

Finding the right mouse with side buttons can transform how you interact with your computer. Whether you play complex MMO games or manage spreadsheets, having extra programmable keys at your fingertips improves efficiency significantly. This guide explores the best options available today.

We have analyzed ten highly rated models from leading brands like Razer, Logitech, and Redragon. Our comparison focuses on sensor precision, button layout, build quality, and software customization. Each product was selected based on user feedback and technical specifications.

Each pick in this list highlights specific strengths tailored to different user needs and budget ranges. You will find detailed reviews, pros and cons, and key specifications for every model. Please note that prices and availability may change frequently on retailer sites.

Top 3 Picks for Best Mouse with Side Buttons

Top 10 Best Mouse with Side Buttons in 2026 Compared

This table provides a quick side-by-side comparison of all ten models featured in this guide. You can easily see the key specifications, button counts, and sensor capabilities for each option at a glance.

1. Razer Naga V2 HyperSpeed – Best Overall Mouse with Side Buttons

4.0Editor scoreCheck price on Amazon

Razer Naga V2 HyperSpeed

19 programmable buttons

Focus Pro 30K sensor

HyperSpeed Wireless

400 hour battery life

The Razer Naga V2 HyperSpeed stands out as a top-tier option for gamers who need extensive command mapping. With a rating of 4.0 stars, it delivers reliability and performance for serious players who demand precision and customization in their peripheral setup.

Pros

• Massive button count for macros
• Long battery life
• Versatile connectivity options
• High precision sensor

Cons

• Higher price point
• Large footprint

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This mouse features nineteen programmable buttons that allow you to map complex macros and skills directly to your thumb. The Focus Pro 30K optical sensor ensures flawless tracking on various surfaces, while the wireless technology provides low latency comparable to wired connections.

While the battery life is impressive at up to four hundred hours on Bluetooth, the device is on the larger side which might not suit smaller hands. However, the ability to switch between HyperSpeed wireless and Bluetooth offers flexibility that many competitors lack.

If you play MMOs or MOBA games heavily, this mouse is an excellent investment. The ergonomics support long sessions, and the software integration allows for deep customization. It is recommended for users who prioritize button count and wireless freedom.

Unmatched Button Customization

The nineteen buttons provide unparalleled access to in-game actions without needing to switch windows or use keyboard combos.

Extended Wireless Usage

With hundreds of hours of battery life, you can game for weeks without needing to recharge or replace batteries.

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2. Redragon M901K – Best Budget Mouse with Side Buttons

4.4Editor scoreCheck price on Amazon

Redragon Gaming Mouse M901K

19 macro programmable buttons

12400 DPI sensor

RGB lighting modes

Adjustable weight tuning

The Redragon M901K is a fantastic choice for budget-conscious gamers who do not want to sacrifice features. With a 4.4 rating, it offers a high number of programmable buttons and a solid sensor that performs well for most gaming scenarios.

Pros

• Excellent value for money
• Large number of side buttons
• Customizable weight system
• Durable build quality

Cons

• Wired connection only
• Software learning curve

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This model includes nineteen macro programmable buttons that can be remapped to suit your specific gameplay needs. The adjustable DPI and polling rate ensure smooth movements, while the weight tuning system lets you balance the mouse to your preference.

The main drawback is that it relies on a wired connection which limits mobility compared to wireless options. However, for stationary gaming setups, the cable provides a stable connection without battery concerns. The RGB lighting adds a nice aesthetic touch.

We recommend this mouse for players who want a feature-rich experience without breaking the bank. It is particularly good for those transitioning from basic mice who need more control over their inputs. The ergonomic design helps reduce fatigue over time.

Affordable Customization

Get a high number of programmable buttons and RGB lighting at a fraction of the cost of premium competitors.

Personalized Balance

Remove or add weights to find the exact feel and balance that suits your grip style and hand size.

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3. Razer Naga V3 Pro – Best Premium Mouse with Side Buttons

4.2Editor scoreCheck price on Amazon

Razer Naga V3 Pro

Swappable side plates

50K optical sensor

HyperSpeed wireless

155 hour battery life

The Razer Naga V3 Pro represents the pinnacle of MMO mouse design with its unique swappable side plates. Rated at 4.2 stars, it allows you to adapt the mouse to different game genres by changing the button layout on the fly.

Pros

• Versatile side plates for any game
• Highest sensor resolution available
• Premium build quality
• Advanced scroll wheel

Cons

• Very expensive
• Heavy when fully loaded

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With a Focus Pro 50K optical sensor, this mouse offers the highest precision available in the market. The HyperScroll tilt wheel provides dual tactile modes for enhanced feedback, and the wireless connectivity ensures seamless performance during intense gaming sessions.

The price point is significantly higher than most other options, which might be a barrier for some users. Additionally, the mouse can feel heavy if all plates are attached. Despite this, the versatility and performance justify the cost for enthusiasts.

This mouse is ideal for players who switch between genres like MMOs, MOBAs, and FPS games frequently. The ability to customize the side plate means you always have the right layout for the task. It is a top choice for serious gamers.

Adaptable Layouts

Swap between twelve, six, or two-button plates to match the specific requirements of your current game.

Top Tier Precision

The 50K sensor tracks movement with incredible accuracy, ensuring your cursor lands exactly where you intend.

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4. Redragon M901P-KS – Reliable Wireless Option

4.4Editor scoreCheck price on Amazon

Redragon Wireless Gaming M901P-KS

16 programmable buttons

16000 DPI sensor

70 hours battery

Wired charging support

The Redragon M901P-KS offers a wireless alternative to its wired counterpart with strong performance metrics. Holding a 4.4 rating, it provides sixteen programmable buttons and a robust sensor that supports high-speed movements without lag or jitter issues.

Pros

• Wireless convenience
• Good battery life
• Remappable buttons
• Comfortable ergonomics

Cons

• Battery drains with RGB
• Slightly heavier

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It features a built-in battery that lasts up to seventy hours with RGB off, which is suitable for most daily gaming sessions. You can continue using the mouse while charging via the USB cable, ensuring you are never left without a tool.

The wireless technology can introduce slight latency in competitive scenarios compared to wired mice, but it is minimal for casual use. The RGB lighting is vibrant but consumes battery faster. Overall, it is a balanced choice for wireless MMO gaming.

We suggest this model for those who want the freedom of wireless without paying premium prices. It works well for players who value button customization and ergonomic comfort. The ability to switch modes with one click adds to its usability.

Wireless Freedom

Eliminate cable clutter and experience smoother movements with a wireless design that maintains professional performance standards.

Rechargeable Power

Never run out of power mid-game with a rechargeable battery that supports usage even while connected via cable.

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5. Razer DeathAdder Essential – Best Standard Ergonomic

4.5Editor scoreCheck price on Amazon

Razer DeathAdder Essential

5 programmable buttons

6400 DPI sensor

Ergonomic design

Mechanical switches

The Razer DeathAdder Essential is a classic choice for those who prioritize comfort over complex features. With a 4.5 rating, it is one of the most comfortable mice on the market, making it ideal for long work or gaming sessions.

Pros

• Highly ergonomic shape
• Affordable price
• Reliable switches
• Simple to use

Cons

• Few side buttons
• Basic sensor specs

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Although it has fewer buttons than full MMO mice, it offers five programmable buttons that can handle most common tasks. The optical sensor provides on-the-fly DPI adjustments, and the mechanical switches are durable enough to withstand millions of clicks.

It lacks the extensive side button panel found in other models here, which limits macro capabilities. However, for players who prefer simplicity and hand support, this trade-off is acceptable. The design is timeless and fits most hand sizes well.

This mouse is recommended for users who want a dependable ergonomic option without paying too much. It is great for FPS gamers or office workers who need reliability. The ridged scroll wheel ensures precise scrolling when you need it most.

Comfort First Design

The ergonomic shape supports your hand naturally to reduce strain during extended periods of use.

Durable Switches

Mechanical switches rated for ten million clicks ensure that your primary actions remain consistent over time.

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6. UtechSmart Venus Pro – Strong Mid-Range MMO Mouse

4.4Editor scoreCheck price on Amazon

UtechSmart Venus Pro

12 side buttons

16400 DPI sensor

RGB lighting

Weight adjustable

The UtechSmart Venus Pro is a solid contender for MMO players seeking high performance at a reasonable price. It features a 4.4 rating and includes twelve side buttons that are angled for easy access by your thumb during gameplay.

Pros

• High DPI sensor
• Comfortable thumb rest
• Customizable profiles
• Durable cable

Cons

• Older design aesthetic
• Software can be complex

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The sensor offers up to 16400 DPI which is more than sufficient for most gaming needs. You can adjust the sensitivity easily using the buttons on the mouse. The included weights allow you to tune the mouse to your preferred feel.

The design is a bit dated compared to newer models but it remains functional and comfortable. The braided fiber cable adds durability, though it might be stiff for some users. The RGB lighting helps identify different profiles quickly.

We recommend this mouse for users who want a dedicated MMO tool without overspending. It works well for games that require frequent skill activation. The macro features allow for complex combos that can give you an edge.

Thumb-Friendly Layout

The angled side buttons are positioned specifically to be reached easily by your thumb without shifting grip.

Profile Management

Save multiple custom profiles to handle different games or tasks without reprogramming every time.

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7. AFUNTA C12 – Affordable Entry-Level MMO Mouse

4.3Editor scoreCheck price on Amazon

AFUNTA C12

12 side buttons

8000 DPI sensor

6 color modes

Built-in weights

The AFUNTA C12 is an excellent entry point for those wanting side buttons without a high cost. It has a 4.3 rating and offers twelve programmable buttons which are sufficient for basic macros and navigation tasks.

Pros

• Very affordable
• Decent button count
• Comfortable shape
• Simple functionality

Cons

• Lower DPI than others
• Basic lighting

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The sensor supports up to 8000 DPI which is adequate for most monitors. It features a triple click fire key that can help with speed in certain games. The weights inside can be adjusted to match your habit and preference.

The DPI levels are fixed at four steps rather than fully adjustable which limits fine tuning. However, for casual players or those on a strict budget, this does not impact much utility. The build feels sturdy for the price.

This mouse is best for students or casual gamers who need extra keys for shortcuts or basic gaming. It is easy to set up and use immediately. If you need extreme precision, you might look elsewhere but for value it is strong.

Triple Click Fire Key

A dedicated triple click button helps you execute rapid actions quickly without needing multiple clicks manually.

Affordable Features

Get a significant number of programmable buttons and LED modes at a price point that is hard to beat.

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8. Razer Basilisk V3 – Best All-Rounder for Productivity

4.6Editor scoreCheck price on Amazon

Razer Basilisk V3

11 programmable buttons

26K DPI sensor

Chroma RGB

HyperScroll tilt wheel

The Razer Basilisk V3 is a top-rated choice for mixed use in gaming and productivity with a 4.6 rating. Its hyper-scroll tilt wheel allows you to switch between precise ratcheting and free-spin modes instantly for different tasks.

Pros

• Versatile scroll wheel
• High resolution sensor
• Thumb rest design
• Strong software

Cons

• Wired only
• RGB consumes power

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It includes eleven programmable buttons that cover most essential actions. The optical switches provide a fast actuation speed which helps in competitive titles. The ergonomic shape with a thumb rest ensures comfort during long work sessions.

Being wired is a limitation for some users who prefer wireless setups. The RGB lighting is beautiful but adds to the cable management complexity. However, the sensor and wheel features make it stand out as a versatile tool.

We recommend this mouse for users who want a reliable all-rounder that handles both work and play. The software allows for deep customization. If you do not need MMO specific layouts, this is a superior option.

HyperScroll Tilt Wheel

Swipe the scroll wheel to toggle between infinite scrolling for long documents and precise ratcheting for accuracy.

Thumb Rest Comfort

The dedicated thumb rest supports your hand ergonomically to reduce strain over hours of use.

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9. Logitech Signature M650 – Best for Office Productivity

4.6Editor scoreCheck price on Amazon

Logitech Signature M650

Customizable side buttons

SmartWheel

24 month battery

SilentTouch

The Logitech Signature M650 is designed for comfort and productivity with a 4.6 rating. It features customizable side buttons that can be set to common shortcuts like copy paste or navigation to improve your workflow.

Pros

• Silent clicks
• Long battery life
• Comfortable grip
• Multi-platform support

Cons

• Limited gaming features
• Side buttons basic

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Its SmartWheel allows you to switch between line-by-line scrolling and hyper-fast scrolling with a flick. The silent touch technology reduces click noise by 90 percent making it suitable for quiet offices. The battery lasts up to two years.

While it is not built for intense gaming, it is perfect for general work tasks. The rubber side grips ensure a snug fit for small to medium hands. The multi-device connectivity allows you to switch between computers easily.

We recommend this mouse for office workers who want a comfortable and efficient tool. It excels at document management and web navigation. If you need side buttons for productivity rather than gaming, this is a top choice.

Quiet Operation

SilentTouch technology ensures that your clicks do not disturb others around you in shared environments.

Efficient Scrolling

The SmartWheel adjusts scrolling speed based on how you use it to match your document navigation style.

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10. Logitech G502 X Plus – Best High-End Wireless Gaming

4.4Editor scoreCheck price on Amazon

Logitech G502 X Plus

Hybrid switches

25K gaming sensor

Lightspeed wireless

Dual-mode scroll

The Logitech G502 X Plus reimagines a popular legacy design with modern technology and wireless freedom. It has a 4.4 rating and features lightforce switches that combine optical and mechanical benefits for speed and reliability.

Pros

• Lightforce switches
• Wireless reliability
• Dual scroll modes
• Modern design

Cons

• Expensive
• Few side buttons than MMO

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It includes dual-mode scroll wheel and reversible DPI-shift button for customization. The wireless connection is extremely responsive with no lag. The sensor tracks with high precision ensuring pixel accuracy during gameplay or design work.

The price is high which makes it a premium investment. It has fewer side buttons than dedicated MMO mice which limits macro utility. However for general gaming it provides a balanced experience. The RGB lighting is subtle and customizable.

This mouse is ideal for gamers who want a modern upgrade to a classic shape. It works well for shooters and strategy games. If you value wireless quality and build precision this is one of the best available options.

Hybrid Optical Switches

These switches offer crisp feedback with zero misclicks thanks to the hybrid technology for long-term durability.

Versatile Scroll Wheel

Switch between free spin for speed and ratcheting for accuracy depending on the task you are performing.

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Buying Guide – How to Choose the Best Mouse with Side Buttons

Selecting the right mouse with side buttons requires understanding your specific needs and preferences. This guide outlines the key factors to consider to ensure you make an informed decision.

Button Layout and Count

The number and arrangement of side buttons determine how many commands you can access quickly. MMO games benefit from twelve buttons while other tasks might need fewer. Consider how many macros you typically use.

Choose a layout that matches your gaming habits or workflow. More buttons provide flexibility but can be complex to learn. Ensure the buttons are positioned comfortably for your thumb.

Sensor Accuracy and DPI

The sensor quality affects tracking precision and cursor accuracy. High DPI settings allow for faster movements on large screens. Optical sensors generally offer better performance than laser ones for gaming.

Look for a mouse with adjustable DPI to switch between speed and precision easily. A high polling rate ensures your movements are registered without delay.

Wired vs Wireless

Wired mice provide stable connections without battery concerns which is ideal for competitive gaming. Wireless mice offer freedom of movement and reduced desk clutter. Modern wireless tech has low latency suitable for most games.

Decide if you prioritize mobility or absolute stability. Wireless mice require charging or batteries so consider the convenience factor.

Ergonomics and Comfort

The shape of the mouse should support your hand to prevent strain during long sessions. Look for textured grips and thumb rests if you have larger hands. Ergonomic designs reduce fatigue significantly.

Try to test the mouse if possible to ensure it fits your grip style. A comfortable shape will improve performance over time.

Software Customization

Robust software allows you to program macros and manage button assignments effectively. Some brands offer advanced profile management for different applications. Check if the software supports your operating system.

Software that is intuitive and stable is crucial for using side buttons efficiently. Avoid mice with outdated or buggy configuration tools.

Battery Life and Charging

For wireless models battery life is a major factor. Look for options that last hundreds of hours on a single charge. Some mice support use while charging which adds convenience.

Consider if the battery is removable or internal. A long battery life ensures you do not have to charge frequently.

Build Quality and Durability

The materials used in construction impact longevity and feel. Switches rated for millions of clicks will last longer. A solid build prevents flexing during aggressive use.

Check for warranties and manufacturing quality. Durable mice save money in the long run and perform consistently.

Price and Value

Prices vary widely based on features and brand reputation. Budget options can offer many buttons but might lack premium sensors. High-end models provide superior build and software.

Balance your budget with your needs. Sometimes a mid-range mouse offers the best value for casual or hybrid users.

How to Use and Care for Your Mouse with Side Buttons

To maximize efficiency configure your side buttons using the provided software. Assign macros or shortcuts that you use frequently to reduce reliance on the keyboard. This saves time during gaming or complex tasks.

Keep the mouse surface clean to ensure smooth tracking. Dust and debris can accumulate on the feet or sensor lens reducing performance. Wipe the bottom with a soft dry cloth regularly.

Adjust the settings to fit your grip style. If the mouse is wireless keep the charging cable handy for long sessions. Update the firmware periodically to maintain compatibility with new applications.

Frequently Asked Questions

Final Thoughts on Choosing the Best Mouse with Side Buttons

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